Assay Detail
Functional
CHEMBL5241642
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human ME-180 cells assessed as inhibition of cell growth by [3H]-thymidine incorporation based liquid scintillation counter analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ME-180 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Overview of all-trans-retinoic acid (ATRA) and its analogues: Structures, activities, and mechanisms in acute promyelocytic leukaemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89241 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89241 | — | IC50 | = | 1.0 | nM | 9.00 |