Assay Detail
Binding
CHEMBL5241794
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at PPARalpha (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL239) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.53 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | 4.0 | 1 | 6.24 |
| CHEMBL5268158 | — | — | 1 | 6.04 |
| CHEMBL445740 | BETA-CARYOPHYLLENE | 1.0 | 1 | 5.02 |
| CHEMBL150 | KAEMPFEROL | 1.0 | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295124 | BERBERINE | EC50 | = | 580.0 | nM | 6.24 |
| CHEMBL5268158 | — | EC50 | = | 906.0 | nM | 6.04 |
| CHEMBL445740 | BETA-CARYOPHYLLENE | EC50 | = | 9580.0 | nM | 5.02 |
| CHEMBL150 | KAEMPFEROL | EC50 | = | 15500.0 | nM | 4.81 |