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Assay Detail

CHEMBL5241815

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against DENV2 infected in African green monkey Vero E6 cells assessed as inhibition of viral replication incubated for 5 days by crystal violet staining based plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism dengue virus type 2
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

dengue virus type 2 (CHEMBL613966)
Type ORGANISM
Organism dengue virus type 2

Publication

Dengue structural proteins as antiviral drug targets: Current status in the drug discovery & development.
S AH, Pujar GV, Sethu AK, Bhagyalalitha M, Singh M.
Eur J Med Chem (2021) 221 : 113527 -113527
PubMed 34020338 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.76 5.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL506069 GERANIIN 1 5.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL506069 GERANIIN IC50 = 1750.0 nM 5.76