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Assay Detail

CHEMBL5242010

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of P-selectin (unknown origin) incubated for 30 mins by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

P-selectin (CHEMBL5378)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins.
Sethi A, Sanam S, Alvala M.
Eur J Med Chem (2021) 222 : 113561 -113561
PubMed 34146913 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.65 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5269430 1 6.52
CHEMBL293171 1 4.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5269430 IC50 = 300.0 nM 6.52
CHEMBL293171 IC50 = 17000.0 nM 4.77