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Assay Detail

CHEMBL5242756

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to EP2 (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prostaglandin E2 receptor EP2 subtype (CHEMBL1881)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.
Wu X, Yang X, Liang Q, Xue X, Huang J, Wang J, Xu Y, Tong R, Liu M, Zhou Q, Shi J.
Eur J Med Chem (2021) 226 : 113842 -113842
PubMed 34536672 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.44 8.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3707245 OMIDENEPAG 2.0 1 8.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3707245 OMIDENEPAG Ki = 3.6 nM 8.44