Assay Detail

CHEMBL5242757

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Functional

Antiglaucoma activity in ocular hypersensitive monkey assessed as reduction in intraocular pressure

ChEMBL ↗

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Target

Rhesus monkey (CHEMBL614875) ↗

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Primary target Rhesus monkey

CHEMBL614875

Anchored from Assay target.

Protein identity Rhesus monkey

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Macaca mulatta
Confidence	1 — Organism
Curated By	Autocuration

Target

Rhesus monkey (CHEMBL614875) ↗

Type	ORGANISM
Organism	Macaca mulatta

Publication

Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.

Wu X, Yang X, Liang Q, Xue X, Huang J, Wang J, Xu Y, Tong R, Liu M, Zhou Q, Shi J.
Eur J Med Chem (2021) 226 : 113842 -113842
PubMed 34536672 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.08	8.08

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3707245	OMIDENEPAG	2.0	1	8.08

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3707245	OMIDENEPAG	EC50	=	8.3	nM	8.08