Assay Detail
Functional
CHEMBL5242768
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of disruption of actin stress fibers in PTM cells by actin stress fiber assay
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sus scrofa |
| Cell Type | PTM cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.76 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4753043 | NETARSUDIL-M1 | -1.0 | 2 | 8.52 |
| CHEMBL4594250 | NETARSUDIL | 4.0 | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4753043 | NETARSUDIL-M1 | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4753043 | NETARSUDIL-M1 | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL4594250 | NETARSUDIL | IC50 | = | 79.0 | nM | 7.10 |