Assay Detail
Functional
CHEMBL5242769
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of disruption of actin stress fibers in human TM1 cells by actin stress fiber assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TM1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.80 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4594250 | NETARSUDIL | 4.0 | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4594250 | NETARSUDIL | IC50 | = | 16.0 | nM | 7.80 |