Assay Detail
Binding
CHEMBL5243222
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli topoisomerase 4 assessed as reduction in decatenation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.55 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5277862 | — | — | 1 | 6.62 |
| CHEMBL5287867 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5277862 | — | IC50 | = | 237.0 | nM | 6.62 |
| CHEMBL5287867 | — | IC50 | = | 341.0 | nM | 6.47 |