Assay Detail
Functional
CHEMBL5243295
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Anticancer activity against human NUGC cells assessed as cell growth inhibition incubated for 24 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NUGC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.75 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17289 | CHS-828 | 1.0 | 1 | 7.60 |
| CHEMBL5268029 | — | — | 1 | 7.26 |
| CHEMBL5267417 | — | — | 1 | 6.48 |
| CHEMBL5284873 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17289 | CHS-828 | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL5268029 | — | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL5267417 | — | IC50 | = | 328.0 | nM | 6.48 |
| CHEMBL5284873 | — | IC50 | = | 2208.0 | nM | 5.66 |