Assay Detail
Binding
CHEMBL5243584
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of soybean 15-LOX
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo[1,5-<i>a</i>]pyrimidine scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.95 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5280862 | — | — | 1 | 5.25 |
| CHEMBL5267419 | — | — | 1 | 5.09 |
| CHEMBL5266517 | — | — | 1 | 5.08 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | 5.07 |
| CHEMBL5278118 | — | — | 1 | 4.85 |
| CHEMBL5275045 | — | — | 1 | 4.74 |
| CHEMBL5274868 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5280862 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL5267419 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL5266517 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL5278118 | — | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL5275045 | — | IC50 | = | 18400.0 | nM | 4.74 |
| CHEMBL5274868 | — | IC50 | = | 27300.0 | nM | 4.56 |