Assay Detail

CHEMBL5243769

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Functional

Inhibition of cell growth in human LoVo cells by SRB assay

ChEMBL ↗

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Target

LoVo (CHEMBL614721) ↗

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Primary target LoVo

CHEMBL614721

Anchored from Assay target.

Protein identity LoVo

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	LoVo
Confidence	1 — Organism
Curated By	Autocuration

Target

LoVo (CHEMBL614721) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

A concise review on marine bromopyrrole alkaloids as anticancer agents.

Mahamed S, Motal R, Govender T, Dlamini N, Khuboni K, Hadeb Z, Shaik BB, Moodley K, Balaso Mohite S, Karpoormath R.
Bioorg Med Chem Lett (2023) 80 : 129102 -129102
PubMed 36496202 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	8.37	8.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL359106	—	—	1	8.52
CHEMBL361708	HYMENIALDISINE	—	1	8.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL359106	—	IC50	=	3.0	nM	8.52
CHEMBL361708	HYMENIALDISINE	IC50	=	6.0	nM	8.22