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Assay Detail

CHEMBL5243796

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human WRL68 cells by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type WRL68
Confidence 1 — Organism
Curated By Autocuration

Target

WRL68 (CHEMBL612587)
Type CELL-LINE
Organism Homo sapiens

Publication

A concise review on marine bromopyrrole alkaloids as anticancer agents.
Mahamed S, Motal R, Govender T, Dlamini N, Khuboni K, Hadeb Z, Shaik BB, Moodley K, Balaso Mohite S, Karpoormath R.
Bioorg Med Chem Lett (2023) 80 : 129102 -129102
PubMed 36496202 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 7.54 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5275970 1 8.00
CHEMBL5274188 1 7.52
CHEMBL5272977 1 7.52
CHEMBL5287188 1 7.52
CHEMBL5267231 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5275970 IC50 = 10.0 nM 8.00
CHEMBL5274188 IC50 = 30.0 nM 7.52
CHEMBL5272977 IC50 = 30.0 nM 7.52
CHEMBL5287188 IC50 = 30.0 nM 7.52
CHEMBL5267231 IC50 = 70.0 nM 7.16