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Assay Detail

CHEMBL5243798

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate reader
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

72 kDa type IV collagenase (CHEMBL333)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A concise review on marine bromopyrrole alkaloids as anticancer agents.
Mahamed S, Motal R, Govender T, Dlamini N, Khuboni K, Hadeb Z, Shaik BB, Moodley K, Balaso Mohite S, Karpoormath R.
Bioorg Med Chem Lett (2023) 80 : 129102 -129102
PubMed 36496202 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.75 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5272977 1 5.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5272977 IC50 = 1800.0 nM 5.75