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Assay Detail

CHEMBL5244334

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Binding
Binding affinity to rat albumin assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Albumin (CHEMBL4817)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics.
Zorzi A, Linciano S, Angelini A.
Medchemcomm (2019) 10 : 1068 -1081
PubMed 31391879 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.68 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5267643 1 6.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5267643 Kd = 210.0 nM 6.68