Assay Detail
Functional
CHEMBL5244997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by CCK-8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
l,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.97 | 5.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL490796 | — | — | 1 | 5.69 |
| CHEMBL5290882 | — | — | 1 | 4.98 |
| CHEMBL5280694 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL490796 | — | IC50 | = | 2040.0 | nM | 5.69 |
| CHEMBL5290882 | — | IC50 | = | 10410.0 | nM | 4.98 |
| CHEMBL5280694 | — | IC50 | = | 56620.0 | nM | 4.25 |