Assay Detail
Functional
CHEMBL5245070
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B reagent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Malme-3M |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
l,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.96 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5274027 | — | — | 1 | 6.96 |
| CHEMBL5280123 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5274027 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5280123 | — | IC50 | = | 110.0 | nM | 6.96 |