Assay Detail

CHEMBL5245367

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiproliferative activity against human leukaemia cell line

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	leukaemia cell line
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Artemisinin-derived hybrids and their anticancer activity.

Gao F, Sun Z, Kong F, Xiao J.
Eur J Med Chem (2020) 188 : 112044 -112044
PubMed 31945642 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.26	7.26

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5286285	—	—	1	7.26
CHEMBL269671	ARTEMISININ	3.0	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5286285	—	IC50	=	55.0	nM	7.26
CHEMBL269671	ARTEMISININ	IC50	>=	40000.0	nM	-