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Assay Detail

CHEMBL5245422

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Functional
Antiproliferative activity against human HT-29 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Artemisinin-derived hybrids and their anticancer activity.
Gao F, Sun Z, Kong F, Xiao J.
Eur J Med Chem (2020) 188 : 112044 -112044
PubMed 31945642 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.26 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5269153 1 7.77
CHEMBL5286627 1 7.60
CHEMBL5286662 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5269153 IC50 = 17.0 nM 7.77
CHEMBL5286627 IC50 = 25.0 nM 7.60
CHEMBL5286662 IC50 = 380.0 nM 6.42