Assay Detail
Functional
CHEMBL5245591
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human RPMI-7951 cells measured after 72 hrs by microplate reader analysis
10
Total Activities
10
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RPMI-7951 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| GI50 | 8 | - | - |
| IC50 | 2 | 6.11 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5269612 | — | — | 1 | 6.16 |
| CHEMBL5270057 | — | — | 1 | 6.05 |
| CHEMBL559673 | — | — | 1 | - |
| CHEMBL4160174 | — | — | 1 | - |
| CHEMBL129134 | — | — | 1 | - |
| CHEMBL5269263 | — | — | 1 | - |
| CHEMBL477053 | — | — | 1 | - |
| CHEMBL1997863 | — | — | 1 | - |
| CHEMBL5275021 | — | — | 1 | - |
| CHEMBL4177177 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5269612 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL5270057 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL559673 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL4160174 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL129134 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL5269263 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL477053 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL1997863 | — | GI50 | = | 2300.0 | nM | - |
| CHEMBL5275021 | — | GI50 | = | 800.0 | nM | - |
| CHEMBL4177177 | — | GI50 | = | 800.0 | nM | - |