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Assay Detail

CHEMBL5245648

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Functional
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell growth
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Autocuration

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Moreira J, Saraiva L, Pinto MM, Cidade H.
Eur J Med Chem (2020) 192 : 112177 -112177
PubMed 32172081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2079269 1 6.52
CHEMBL5282230 1 6.52
CHEMBL2297363 1 6.52
CHEMBL2386416 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2079269 IC50 = 300.0 nM 6.52
CHEMBL5282230 IC50 = 300.0 nM 6.52
CHEMBL2297363 IC50 = 300.0 nM 6.52
CHEMBL2386416 IC50 = 300.0 nM 6.52