Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5245652

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Antiproliferative activity against human MCF-10A cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type MCF-10A
Confidence 1 — Organism
Curated By Autocuration

Target

MCF-10A (CHEMBL614321)
Type CELL-LINE
Organism Homo sapiens

Publication

Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Moreira J, Saraiva L, Pinto MM, Cidade H.
Eur J Med Chem (2020) 192 : 112177 -112177
PubMed 32172081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.39 4.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5289537 1 4.39
CHEMBL1186460 1 4.39
CHEMBL1190487 1 4.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5289537 IC50 = 41030.0 nM 4.39
CHEMBL1186460 IC50 = 41030.0 nM 4.39
CHEMBL1190487 IC50 = 41030.0 nM 4.39