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Assay Detail

CHEMBL5245653

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Functional
Antiproliferative activity against human HEp-2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEp-2
Confidence 1 — Organism
Curated By Autocuration

Target

HEp-2 (CHEMBL614735)
Type CELL-LINE
Organism Homo sapiens

Publication

Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Moreira J, Saraiva L, Pinto MM, Cidade H.
Eur J Med Chem (2020) 192 : 112177 -112177
PubMed 32172081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.78 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4167818 1 4.78

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4167818 IC50 = 16590.0 nM 4.78