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Assay Detail

CHEMBL5245668

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Functional
Antiproliferative activity against lung metastasis variant of human MDA-MB-231 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Moreira J, Saraiva L, Pinto MM, Cidade H.
Eur J Med Chem (2020) 192 : 112177 -112177
PubMed 32172081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.28 6.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5289537 1 6.28
CHEMBL1186460 1 6.28
CHEMBL1190487 1 6.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5289537 IC50 = 530.0 nM 6.28
CHEMBL1186460 IC50 = 530.0 nM 6.28
CHEMBL1190487 IC50 = 530.0 nM 6.28