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Assay Detail

CHEMBL5245673

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Functional
Inhibition of cell migration in mouse B16-F10 cells by wound healing assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type B16-F10
Confidence 1 — Organism
Curated By Autocuration

Target

B16-F10 (CHEMBL612656)
Type CELL-LINE
Organism Mus musculus

Publication

Antitumor activity and structure-activity relationship of heparanase inhibitors: Recent advances.
Fu K, Bai Z, Chen L, Ye W, Wang M, Hu J, Liu C, Zhou W.
Eur J Med Chem (2020) 193 : 112221 -112221
PubMed 32222663 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.67 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3347523 1 4.82
CHEMBL5275830 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3347523 IC50 = 15000.0 nM 4.82
CHEMBL5275830 IC50 = 30000.0 nM 4.52