Assay Detail
Functional
CHEMBL5245702
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Antiproliferative activity against human A549 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.88 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5265783 | — | — | 1 | 7.70 |
| CHEMBL5272362 | — | — | 1 | 5.10 |
| CHEMBL5278667 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5265783 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5272362 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL5278667 | — | IC50 | = | 14000.0 | nM | 4.85 |