Assay Detail
Binding
CHEMBL5245779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human alpha A1 adrenoreceptor expressed in CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry: A review of its recent applications in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.32 | 9.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1182155 | — | — | 1 | 9.39 |
| CHEMBL1182182 | — | — | 1 | 8.80 |
| CHEMBL1182191 | — | — | 1 | 7.60 |
| CHEMBL1182152 | — | — | 1 | 7.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1182155 | — | Ki | = | 0.4074 | nM | 9.39 |
| CHEMBL1182182 | — | Ki | = | 1.585 | nM | 8.80 |
| CHEMBL1182191 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1182152 | — | Ki | = | 33.88 | nM | 7.47 |