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Assay Detail

CHEMBL5246090

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HT-29 cells assessed as cell viability incubated for 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species.
He L, Su Q, Bai L, Li M, Liu J, Liu X, Zhang C, Jiang Z, He J, Shi J, Huang S, Guo L.
Eur J Med Chem (2020) 204 : 112530 -112530
PubMed 32711292 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.35 4.53

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5266156 1 4.53
CHEMBL5278132 1 4.52
CHEMBL5265982 1 4.28
CHEMBL5282250 1 4.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5266156 IC50 = 29300.0 nM 4.53
CHEMBL5278132 IC50 = 30400.0 nM 4.52
CHEMBL5265982 IC50 = 52000.0 nM 4.28
CHEMBL5282250 IC50 = 88200.0 nM 4.05