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Assay Detail

CHEMBL5246116

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Severe acute respiratory syndrome coronavirus 2 infected in African green monkey Vero cells incubated for 24 to 48 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Potential treatment methods targeting 2019-nCoV infection.
Zheng L, Zhang L, Huang J, Nandakumar KS, Liu S, Cheng K.
Eur J Med Chem (2020) 205 : 112687 -112687
PubMed 32771797 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.14 6.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1535 HYDROXYCHLOROQUINE 4.0 1 6.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1535 HYDROXYCHLOROQUINE EC50 = 720.0 nM 6.14