Assay Detail
Functional
CHEMBL5246472
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Antiviral activity against HBV harboring core protein V124F mutant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and optimization of benzenesulfonamides-based hepatitis B virus capsid modulators via contemporary medicinal chemistry strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.04 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4533071 | — | — | 1 | 6.54 |
| CHEMBL4446995 | — | — | 1 | 5.96 |
| CHEMBL605300 | — | — | 1 | 5.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4533071 | — | EC50 | = | 289.0 | nM | 6.54 |
| CHEMBL4446995 | — | EC50 | = | 1086.0 | nM | 5.96 |
| CHEMBL605300 | — | EC50 | = | 2332.0 | nM | 5.63 |