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Assay Detail

CHEMBL5246523

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Tritirachium album limber Proteinase K using H-D-CHA -Ala-Arg-AMC.2AcOH as substrate by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Parengyodontium album
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.
Chen QY, Luo D, Seabra GM, Luesch H.
Bioorg Med Chem (2020) 28 : 115756 -115756
PubMed 33002682 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.91 7.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5284383 1 7.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5284383 IC50 = 12.3 nM 7.91