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Assay Detail

CHEMBL5246556

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum 3D7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research.
Ghatpande NG, Jadhav JS, Kaproormath RV, Soliman ME, Shaikh MM.
Bioorg Med Chem (2020) 28 : 115813 -115813
PubMed 33069128 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.41 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4522426 1 6.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4522426 EC50 = 390.0 nM 6.41