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Assay Detail

CHEMBL5246774

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human placenta ETB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Tissue Placenta
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Endothelin receptor type B (CHEMBL1785)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives.
Zheng W, Wang Z, Jiang X, Zhao Q, Shen J.
J Med Chem (2020) 63 : 15153 -15186
PubMed 33314936 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5272983 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5272983 IC50 = 2000.0 nM 5.70