Assay Detail
Functional
CHEMBL5246822
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Antimalarial activity against chloroquine sensitive Plasmodium falciparum FCR-3
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.32 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1172285 | — | — | 1 | 8.89 |
| CHEMBL1170521 | — | — | 1 | 8.85 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 8.85 |
| CHEMBL1170740 | — | — | 1 | 8.34 |
| CHEMBL5282979 | — | — | 1 | 7.75 |
| CHEMBL5271497 | — | — | 1 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1172285 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL1170521 | — | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL1170740 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL5282979 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL5271497 | — | IC50 | = | 58.0 | nM | 7.24 |