Assay Detail
Binding
CHEMBL5247054
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Calcium channel (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.31 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27006 | — | — | 1 | 6.11 |
| CHEMBL52330 | — | — | 1 | 4.92 |
| CHEMBL99055 | — | — | 1 | 4.89 |
| CHEMBL1471 | APREPITANT | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27006 | — | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL52330 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL99055 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1471 | APREPITANT | IC50 | > | 1000.0 | nM | - |