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Assay Detail

CHEMBL5247134

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human dipeptidyl peptidase 4 using Gly-Pro-AMC as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Dipeptidyl peptidase 4 (CHEMBL284)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Wu YJ, Meanwell NA.
J Med Chem (2021) 64 : 9786 -9874
PubMed 34213340 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.32 9.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1186023 1 9.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1186023 IC50 = 0.48 nM 9.32