Assay Detail
Functional
CHEMBL5247136
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antifungal activity against Candida albicans GS
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.35 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630575 | CASPOFUNGIN | 4.0 | 1 | 9.22 |
| CHEMBL3596266 | — | — | 1 | 9.00 |
| CHEMBL5273712 | — | — | 1 | 8.00 |
| CHEMBL3037784 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630575 | CASPOFUNGIN | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL3596266 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL5273712 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL3037784 | — | IC50 | = | 70.0 | nM | 7.16 |