Assay Detail
Binding
CHEMBL5247145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Influenza A virus CEN
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Polymerase acidic protein (CHEMBL1169598) ↗| Type | SINGLE PROTEIN |
| Organism | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) |
Publication
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.44 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297215 | BALOXAVIR | 2.0 | 1 | 8.60 |
| CHEMBL4297503 | BALOXAVIR MARBOXIL | 4.0 | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297215 | BALOXAVIR | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL4297503 | BALOXAVIR MARBOXIL | IC50 | = | 530.0 | nM | 6.28 |