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Assay Detail

CHEMBL5247336

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to SARS CoV Main protease incubated for 10 mins by FRET assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome-related coronavirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Gao K, Wang R, Chen J, Tepe JJ, Huang F, Wei GW.
J Med Chem (2021) 64 : 16922 -16955
PubMed 34798775 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4852855 1 7.28
CHEMBL5287622 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4852855 Ki = 53.0 nM 7.28
CHEMBL5287622 Ki = 53.0 nM 7.28