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Assay Detail

CHEMBL5247337

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS CoV infected in African green monkey Vero E6 cells measured after 48 hrs by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome-related coronavirus
Cell Type Vero E6
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV (CHEMBL4303836)
Type ORGANISM
Organism Severe acute respiratory syndrome-related coronavirus

Publication

Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Gao K, Wang R, Chen J, Tepe JJ, Huang F, Wei GW.
J Med Chem (2021) 64 : 16922 -16955
PubMed 34798775 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4852855 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4852855 EC50 = 600.0 nM 6.22