Assay Detail
Binding
CHEMBL5247341
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Binding affinity to SARS CoV Main protease incubated for 20 mins by reverse-phase HPLC analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.70 | 7.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268911 | — | — | 1 | 7.42 |
| CHEMBL5267356 | — | — | 1 | 7.24 |
| CHEMBL5289454 | — | — | 1 | 7.00 |
| CHEMBL213543 | — | — | 1 | 6.28 |
| CHEMBL5271613 | — | — | 1 | 6.18 |
| CHEMBL1092796 | IGUESTERIN | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268911 | — | Ki | = | 38.0 | nM | 7.42 |
| CHEMBL5267356 | — | Ki | = | 58.0 | nM | 7.24 |
| CHEMBL5289454 | — | Ki | = | 99.0 | nM | 7.00 |
| CHEMBL213543 | — | Ki | = | 520.0 | nM | 6.28 |
| CHEMBL5271613 | — | Ki | = | 660.0 | nM | 6.18 |
| CHEMBL1092796 | IGUESTERIN | Ki | = | 800.0 | nM | 6.10 |