Assay Detail
Functional
CHEMBL5248965
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Antitumor activity against human HeLa cells assessed as cell growth inhibition incubated for 3 days
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural occurrence, bioactivity, and biosynthesis of triene-ansamycins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.94 | 9.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5266756 | — | — | 1 | 9.07 |
| CHEMBL5273056 | — | — | 1 | 8.51 |
| CHEMBL5288353 | — | — | 1 | 7.75 |
| CHEMBL5289854 | — | — | 1 | 7.55 |
| CHEMBL5276226 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5266756 | — | IC50 | = | 0.85 | nM | 9.07 |
| CHEMBL5273056 | — | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL5288353 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL5289854 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL5276226 | — | IC50 | = | 150.0 | nM | 6.82 |