Assay Detail
Functional
CHEMBL5248975
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human HepG2 cells incubated for 72 hrs by SRB calorimetric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural occurrence, bioactivity, and biosynthesis of triene-ansamycins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.35 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209314 | — | — | 1 | 7.00 |
| CHEMBL4204447 | — | — | 1 | 5.69 |
| CHEMBL5275130 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209314 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4204447 | — | IC50 | = | 2040.0 | nM | 5.69 |
| CHEMBL5275130 | — | IC50 | > | 10000.0 | nM | - |