Assay Detail
Functional
CHEMBL5248977
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human PANC-1 cells incubated for 48 to 72 hrs by MTS Assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural occurrence, bioactivity, and biosynthesis of triene-ansamycins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.35 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209314 | — | — | 1 | 7.00 |
| CHEMBL4204447 | — | — | 1 | 5.69 |
| CHEMBL5275130 | — | — | 1 | - |
| CHEMBL4206697 | — | — | 1 | - |
| CHEMBL5266970 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209314 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4204447 | — | IC50 | = | 2040.0 | nM | 5.69 |
| CHEMBL5275130 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4206697 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5266970 | — | IC50 | >= | 10000.0 | nM | - |