Assay Detail
Functional
CHEMBL5248982
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human PANC-1
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural occurrence, bioactivity, and biosynthesis of triene-ansamycins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.11 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017441 | TRIENOMYCIN A | — | 1 | 8.10 |
| CHEMBL4208120 | — | — | 1 | 7.46 |
| CHEMBL4213035 | — | — | 1 | 6.77 |
| CHEMBL4212488 | — | — | 1 | 6.77 |
| CHEMBL5278915 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017441 | TRIENOMYCIN A | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4208120 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL4213035 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL4212488 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5278915 | — | IC50 | = | 340.0 | nM | 6.47 |