Assay Detail
Binding
CHEMBL5250020
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Binding affinity to AhR (unknown origin) assessed as dissociation constant
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview of aryl hydrocarbon receptor ligands in the Last two decades (2002-2022): A medicinal chemistry perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 8.82 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL472031 | — | — | 1 | 10.15 |
| CHEMBL4580482 | — | — | 1 | 9.89 |
| CHEMBL509307 | — | — | 1 | 9.72 |
| CHEMBL1773683 | EZUTROMID | 2.0 | 1 | 7.30 |
| CHEMBL446452 | ARUNDINE | 3.0 | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL472031 | — | Kd | = | 0.07 | nM | 10.15 |
| CHEMBL4580482 | — | Kd | = | 0.13 | nM | 9.89 |
| CHEMBL509307 | — | Kd | = | 0.19 | nM | 9.72 |
| CHEMBL1773683 | EZUTROMID | Kd | = | 50.0 | nM | 7.30 |
| CHEMBL446452 | ARUNDINE | Kd | = | 90.0 | nM | 7.05 |