Assay Detail
Binding
CHEMBL5250021
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at AhR (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview of aryl hydrocarbon receptor ligands in the Last two decades (2002-2022): A medicinal chemistry perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 8.82 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5289699 | — | — | 1 | 11.00 |
| CHEMBL5203882 | — | — | 1 | 10.52 |
| CHEMBL4750416 | — | — | 1 | 8.92 |
| CHEMBL5198290 | — | — | 1 | 8.80 |
| CHEMBL4764225 | — | — | 1 | 8.60 |
| CHEMBL5267667 | — | — | 1 | 7.92 |
| CHEMBL522782 | PROCHLORAZ | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5289699 | — | EC50 | = | 0.01 | nM | 11.00 |
| CHEMBL5203882 | — | EC50 | = | 0.03 | nM | 10.52 |
| CHEMBL4750416 | — | EC50 | = | 1.2 | nM | 8.92 |
| CHEMBL5198290 | — | EC50 | = | 1.6 | nM | 8.80 |
| CHEMBL4764225 | — | EC50 | = | 2.5 | nM | 8.60 |
| CHEMBL5267667 | — | EC50 | = | 12.0 | nM | 7.92 |
| CHEMBL522782 | PROCHLORAZ | EC50 | = | 1000.0 | nM | 6.00 |