Assay Detail
Binding
CHEMBL5250590
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Aspergillus niger amyloglucosidase
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Aspergillus niger |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.75 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270327 | — | — | 1 | 5.35 |
| CHEMBL5272442 | — | — | 1 | 5.28 |
| CHEMBL5283639 | — | — | 1 | 5.28 |
| CHEMBL1230107 | CASUARINE | — | 1 | 5.20 |
| CHEMBL5271350 | — | — | 1 | 4.41 |
| CHEMBL5280822 | — | — | 1 | 4.22 |
| CHEMBL5288100 | — | — | 1 | 4.19 |
| CHEMBL5291395 | — | — | 1 | 4.09 |
| CHEMBL5276707 | — | — | 1 | - |
| CHEMBL5284497 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270327 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL5272442 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL5283639 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL1230107 | CASUARINE | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL5271350 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL5280822 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL5288100 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL5291395 | — | IC50 | = | 81000.0 | nM | 4.09 |
| CHEMBL5276707 | — | IC50 | = | 152000.0 | nM | - |
| CHEMBL5284497 | — | IC50 | = | 167000.0 | nM | - |