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Assay Detail

CHEMBL5250595

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rice alpha-glucosidase using p-nitrophenyl glycoside as substrate by spectrometric method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryza sativa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study.
Li YX, Wang JZ, Shimadate Y, Kise M, Kato A, Jia YM, Fleet GWJ, Yu CY.
Eur J Med Chem (2022) 244 : 114852 -114852
PubMed 36332547 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.32 4.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5272913 1 4.32
CHEMBL4455229 1 -
CHEMBL5269797 1 -
CHEMBL5275098 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5272913 IC50 = 48000.0 nM 4.32
CHEMBL4455229 IC50 = 234000.0 nM -
CHEMBL5269797 IC50 = 771000.0 nM -
CHEMBL5275098 IC50 = 350000.0 nM -