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Assay Detail

CHEMBL5250609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of porcine kidney alpha/alpha-trehalase using p-nitrophenyl glycoside as substrate by spectrometric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Tissue Kidney
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study.
Li YX, Wang JZ, Shimadate Y, Kise M, Kato A, Jia YM, Fleet GWJ, Yu CY.
Eur J Med Chem (2022) 244 : 114852 -114852
PubMed 36332547 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.66 4.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5282409 1 4.66
CHEMBL4455229 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5282409 IC50 = 22000.0 nM 4.66
CHEMBL4455229 IC50 = 124000.0 nM -